Vagus nerve stimulation paired with rehabilitation for upper limb motor function after ischaemic stroke (VNS-REHAB): a randomised, blinded, pivotal, device trial
Dawson J, Liu CY, Francisco GE, Cramer SC, Wolf SL, Dixit A, Alexander J, Ali R, Brown BL, Feng W, et al.
The Lancet · 2021
Key finding
VNS paired with rehabilitation significantly improved upper limb motor function compared to rehabilitation with sham stimulation in chronic stroke patients at 90 days.
- Condition
- Stroke Rehabilitation
- Stimulation
- iVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 108
Cite this study
Dawson, J., Liu, C. Y., Francisco, G. E., Cramer, S. C., Wolf, S. L., Dixit, A., Alexander, J., Ali, R., Brown, B. L., Feng, W., DeMark, L., Hochberg, L. R., Kautz, S. A., Majid, A., O'Dell, M. W., Pierce, D., Prudente, C. N., Redgrave, J., Turner, D. L., … Kimberley, T. J. (2021). Vagus nerve stimulation paired with rehabilitation for upper limb motor function after ischaemic stroke (VNS-REHAB): a randomised, blinded, pivotal, device trial. The Lancet, 397(10284), 1545-1553. https://doi.org/10.1016/S0140-6736(21)00475-X
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Summary by Vagus Research. Always consult the primary source for the authoritative record.