Controlled Clinical TrialiVNSn = 13

Brain blood-flow change with acute vagus nerve stimulation in treatment-refractory major depressive disorder

Conway C, Sheline Y, Chibnall J, Bucholz R, Price J, Gangwani S, Mintun M

Brain Stimulation · 2012

Key finding

PET imaging during acute VNS in treatment-refractory depression revealed blood-flow changes in the right insula, dorsolateral prefrontal cortex and other mood-relevant regions that related to antidepressant response.

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Condition
Neuroimaging
Stimulation
iVNS
Evidence tier
Controlled Clinical Trial
Participants
13
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Cite this study

Conway, C., Sheline, Y., Chibnall, J., Bucholz, R., Price, J., Gangwani, S., & Mintun, M. (2012). Brain blood-flow change with acute vagus nerve stimulation in treatment-refractory major depressive disorder. Brain Stimulation.

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