Cerebral blood flow changes during vagus nerve stimulation for depression
Conway C, Sheline Y, Chibnall J, George M, Fletcher J, Mintun M
Psychiatry Research: Neuroimaging · 2006
Key finding
PET in depressed patients showed acute VNS produced cerebral blood flow changes in limbic and cortical regions implicated in mood regulation.
- Condition
- Neuroimaging
- Stimulation
- iVNS
- Evidence tier
- Observational / Cohort
- Participants
- 4
Cite this study
Conway, C., Sheline, Y., Chibnall, J., George, M., Fletcher, J., & Mintun, M. (2006). Cerebral blood flow changes during vagus nerve stimulation for depression. Psychiatry Research: Neuroimaging.
Related studies in Neuroimaging
Cognitive function and brain activation before and after transcutaneous cervical vagus nerve stimulation in healthy adults: A concurrent tcVNS-fMRI study
Zhang et al. · Frontiers in psychology · 2022 · Randomised Controlled Trial
Optimization of transcutaneous vagus nerve stimulation using functional MRI
Yakunina et al. · Neuromodulation · 2017 · Randomised Controlled Trial
Non-invasive access to the vagus nerve central projections via electrical stimulation of the external ear: fMRI evidence in humans
Frangos et al. · Brain Stimulation · 2015 · Randomised Controlled Trial
The impact of transcutaneous vagus nerve stimulation on anterior cingulate cortex activity in a cognitive control task
Sönmez et al. · Psychophysiology · 2025 · Controlled Clinical Trial
Summary by Vagus Research. Always consult the primary source for the authoritative record.