Transcutaneous Cervical Vagal Nerve Stimulation in Patients with Posttraumatic Stress Disorder (PTSD): A Pilot Study of Effects on PTSD Symptoms and Interleukin-6 Response to Stress
Bremner JD, Wittbrodt MT, Gurel NZ, Shandhi MH, Gazi AH, Jiao Y, Levantsevych OM, Huang M, Beckwith J, Herring I, et al.
Journal of Affective Disorders Reports · 2021
Key finding
Transcutaneous cervical VNS reduced PTSD symptom severity by 17% and attenuated interleukin-6 inflammatory responses to stress in patients with PTSD.
- Condition
- PTSD
- Stimulation
- tcVNS
- Evidence tier
- Controlled Clinical Trial
- Participants
- 25
Cite this study
Bremner, J. D., Wittbrodt, M. T., Gurel, N. Z., Shandhi, M. H., Gazi, A. H., Jiao, Y., Levantsevych, O. M., Huang, M., Beckwith, J., Herring, I., Murrah, N., Driggers, E. G., Ko, Y. A., Alkhalaf, M. L., Soudan, M., Shallenberger, L., Hankus, A. N., Nye, J. A., Park, J., … Inan, O. T. (2021). Transcutaneous Cervical Vagal Nerve Stimulation in Patients with Posttraumatic Stress Disorder (PTSD): A Pilot Study of Effects on PTSD Symptoms and Interleukin-6 Response to Stress. Journal of Affective Disorders Reports, 6, 100190. https://doi.org/10.1016/j.jadr.2021.100190
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Summary by Vagus Research. Always consult the primary source for the authoritative record.