Randomised Controlled TrialtcVNSn = 34

Effects of cervical transcutaneous Vagus Nerve Stimulation (ctVNS) on military cognitive performance during sleep deprivation

Bottenheft C, Fonken YM, Hendrikse LF, Koedijk M, Landman A, Binsch O

Frontiers in Physiology · 2025

Key finding

In sleep-deprived military operators, a brief ctVNS protocol showed no significant benefit on cognitive task performance or a military operational VR task (null result).

Condition
Stress & Performance
Stimulation
tcVNS
Evidence tier
Randomised Controlled Trial
Participants
34
View on DOI

Cite this study

Bottenheft, C., Fonken, Y. M., Hendrikse, L. F., Koedijk, M., Landman, A., & Binsch, O. (2025). Effects of cervical transcutaneous Vagus Nerve Stimulation (ctVNS) on military cognitive performance during sleep deprivation. Frontiers in Physiology, 16. https://doi.org/10.3389/fphys.2025.1542791

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