Vagus nerve stimulation for treatment of partial seizures: 1. A controlled study of effect on seizures
Ben‐Menachem E, Mañon‐Espaillat R, Ristanovic R, Wilder BJ, Stefan H, Mirza W, Tarver WB, Wernicke JF
Epilepsia · 1994
Key finding
In the first major controlled trial of VNS for epilepsy (E03), high-stimulation VNS achieved a 24.5% median reduction in seizure frequency versus 6.1% in the low-stimulation group in drug-resistant partial seizures.
- Condition
- Epilepsy
- Stimulation
- iVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 114
Cite this study
Ben‐Menachem, E., Mañon‐Espaillat, R., Ristanovic, R., Wilder, B. J., Stefan, H., Mirza, W., Tarver, W. B., & Wernicke, J. F. (1994). Vagus nerve stimulation for treatment of partial seizures: 1. A controlled study of effect on seizures. Epilepsia, 35(3), 616-626. https://doi.org/10.1111/j.1528-1157.1994.tb02482.x
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Summary by Vagus Research. Always consult the primary source for the authoritative record.