Transcutaneous Vagus Nerve Stimulation (tVNS) for Treatment of Drug-Resistant Epilepsy: A Randomized, Double-Blind Clinical Trial (cMPsE02)
Bauer S, Baier H, Baumgartner C, Bohlmann K, Fauser S, Graf W, Hillenbrand B, Hirsch M, Last C, Lerche H, et al.
Brain stimulation · 2016
Key finding
Patients completing 20 weeks of 25 Hz taVNS achieved a 34.2% seizure reduction, though the primary superiority endpoint over 1 Hz control was not met.
- Condition
- Epilepsy
- Stimulation
- taVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 76
Cite this study
Bauer, S., Baier, H., Baumgartner, C., Bohlmann, K., Fauser, S., Graf, W., Hillenbrand, B., Hirsch, M., Last, C., Lerche, H., Mayer, T., Schulze-Bonhage, A., Steinhoff, B., Weber, Y., Hartlep, A., Rosenow, F., & Hamer, H. (2016). Transcutaneous Vagus Nerve Stimulation (tVNS) for Treatment of Drug-Resistant Epilepsy: A Randomized, Double-Blind Clinical Trial (cMPsE02). Brain stimulation.
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