Transcutaneous Auricular Vagus Nerve Stimulation for Post-COVID-19 Condition: A Systematic Review and Critical Appraisal of Clinical Evidence
Balan A, Graham G, Herban S, Marcu M, Gheorghe N, Mara G, Rasinar FC, Lascu A, Mot CI, Dan TF, et al.
Journal of Clinical Medicine · 2026
Key finding
Systematic review of taVNS for post-COVID-19 condition rated the efficacy evidence as very low certainty (GRADE); the only adequately blinded RCT found no significant between-group benefit.
- Condition
- Long COVID
- Stimulation
- taVNS
- Evidence tier
- Systematic Review / Meta-Analysis
- Participants
- —
Cite this study
Balan, A., Graham, G., Herban, S., Marcu, M., Gheorghe, N., Mara, G., Rasinar, F. C., Lascu, A., Mot, C. I., Dan, T. F., Mihaicuta, S., & Frent, S. M. (2026). Transcutaneous Auricular Vagus Nerve Stimulation for Post-COVID-19 Condition: A Systematic Review and Critical Appraisal of Clinical Evidence. Journal of Clinical Medicine, 15(11), 4247. https://doi.org/10.3390/jcm15114247
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Summary by Vagus Research. Always consult the primary source for the authoritative record.