Randomised Controlled TrialtaVNSn = 28

Non-invasive vagus nerve stimulation and exercise capacity in healthy volunteers: a randomized trial

Ackland GL, Patel ABU, Miller S, Gutierrez del Arroyo A, Thirugnanasambanthar J, Ravindran JI, Schroth J, Boot J, Caton L, Mein CA, et al.

European Heart Journal · 2025

Key finding

Seven days of transcutaneous auricular VNS increased peak oxygen uptake (VO2peak) by 1.04 mL/kg/min versus no change with sham, alongside a reduced inflammatory response, in healthy volunteers.

Condition
Sports Recovery
Stimulation
taVNS
Evidence tier
Randomised Controlled Trial
Participants
28
View on DOI

Cite this study

Ackland, G. L., Patel, A. B. U., Miller, S., Gutierrez del Arroyo, A., Thirugnanasambanthar, J., Ravindran, J. I., Schroth, J., Boot, J., Caton, L., Mein, C. A., Abbott, T. E. F., & Gourine, A. V. (2025). Non-invasive vagus nerve stimulation and exercise capacity in healthy volunteers: a randomized trial. European Heart Journal, 46(17), 1634-1644. https://doi.org/10.1093/eurheartj/ehaf037

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