Non-invasive vagus nerve stimulation and exercise capacity in healthy volunteers: a randomized trial
Ackland GL, Patel ABU, Miller S, Gutierrez del Arroyo A, Thirugnanasambanthar J, Ravindran JI, Schroth J, Boot J, Caton L, Mein CA, et al.
European Heart Journal · 2025
Key finding
Seven days of transcutaneous auricular VNS increased peak oxygen uptake (VO2peak) by 1.04 mL/kg/min versus no change with sham, alongside a reduced inflammatory response, in healthy volunteers.
Auto-extracted · verification pendingHow we verify
- Condition
- Sports Recovery
- Stimulation
- taVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 28
Share this study
Download the citation card as a PNG, or copy a link to this page.
Cite this study
Ackland, G. L., Patel, A. B. U., Miller, S., Gutierrez del Arroyo, A., Thirugnanasambanthar, J., Ravindran, J. I., Schroth, J., Boot, J., Caton, L., Mein, C. A., Abbott, T. E. F., & Gourine, A. V. (2025). Non-invasive vagus nerve stimulation and exercise capacity in healthy volunteers: a randomized trial. European Heart Journal, 46(17), 1634-1644. https://doi.org/10.1093/eurheartj/ehaf037
Related studies in Sports Recovery
Post-exercise auricular vagus nerve stimulation modulates autonomic and recovery responses in physically inactive young adults: a randomized controlled trial
Ertürk et al. · Scientific Reports · 2026 · Randomised Controlled Trial
Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Hemodynamics and Autonomic Function During Exercise Stress Tests in Healthy Volunteers
Yoshida et al. · Circulation Reports · 2025 · Randomised Controlled Trial
Effects of a single session of noninvasive auricular vagus nerve stimulation on sports performance in elite athletes: an open-label randomized controlled trial
Çalι et al. · Expert review of medical devices · 2024 · Randomised Controlled Trial
Auricular vagal nerve stimulation in peripheral arterial disease patients
Hackl et al. · VASA. Zeitschrift fur Gefasskrankheiten · 2017 · Controlled Clinical Trial
Summary by Vagus Research. Always consult the primary source for the authoritative record.