Condition · Evidence Hub

Vagus Nerve Stimulation for Endometriosis

Does vagus nerve stimulation help with endometriosis? 1 human study has investigated VNS for endometriosis, including 1 controlled trial, published in 2025. The study uses transcutaneous auricular (taVNS) stimulation. Findings vary by study design and population; the study below is ranked by evidence strength so you can weigh the research directly.

1 controlled trial

1
Human Studies
1
controlled trial
75+
Participants
2025–2025
Years Spanned

Evidence by Tier

strongest → weakest

  • 1Controlled clinical trials

Stimulation Method

  • 1taVNS

Research Momentum

1 of 1 study (100%) published since 2022 — an actively growing evidence base.

The studies

1 study · strongest evidence first
  1. Reduced vagal tone in women with adenomyosis

    Zeng et al. · Reproduction & fertility · 2025 · n = 75

    controlled trialstaVNS

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